Novaerus provides the power of plasma

The outbreak of a new coronavirus has confirmed a fact long understood by Irish company Novaerus: we are what we breathe.

The company manufactures and sells patented medical-grade, clean air solutions. Thanks to new partnerships with established distributors across China, its portable air disinfection units are being made available to healthcare facilities in Hubei, Beijing, Shanghai, Zhejiang, Guangzhou City and the Chinese special administrative regions of Hong Kong and Macau.

It comes at a time of growing concern surrounding the recent infectious outbreak caused by a novel coronavirus first identified in Wuhan, Hubei Province, China. Indeed, the Chinese Ambassador to Ireland, Mr He Xiangdong, recently visited Novaerus, who have donated several air dis-infection devices to two hospitals in Wuhan, the Chinese city at the centre of the COVID-19 outbreak; Wuhan Xincheng Hospital and Wuhan Third People’s Hospital.

Among the donation of goods is a Defend 1050 for each facility, the company’s latest innovation in infection control. The Defend 1050 is a mobile solution designed for rapid remediation in large spaces and situations with a high risk of infection.

 

Coranavirus – Covid-19

Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS).

The current outbreak is a new strain that has not previously been identified in humans. It’s not yet clear how easily it spreads from person-to-person. However both MERS and SARS are thought to have spread via respiratory droplets produced when an infected person coughs or sneezes, similar to how influenza and other respiratory pathogens spread.

 

Dealing with virus transmission

“The most difficult disease transmission-route to guard against is airborne because we have very little to protect us when we breathe,” says Dr Kevin Devlin, CEO at WellAir, the parent company of Novaerus. Currently very many people in affected regions – and further afield – have responded by wearing surgical masks.
Yet while masks may help guard against the kind of particulates seen in air pollution, they are ineffective against the much smaller size of viruses.

Cleaning the air is a fundamental component of managing infectious outbreaks. However standalone filtration systems are typically unable to trap tiny viral particles too.

Novaerus’ portable air disinfection and purification units are unique in using a patented plasma technology that kills airborne viruses. Its devices suck air from a room and pass it through patented plasma coils to eradicate viruses.
So destructive is Novaerus’ technology that he likens it to passing bacteria through “a field of lightning – particles get destructed as they pass through.”

The company makes a range of devices, the biggest of which can take in 900 cubic metres of air per hour and is used in large spaces. The smallest takes in 80 cubic metres of air in an hour. All run 24 hours a day, using very low power, and reduce the risk to people coming into and out of that room dramatically.

Its units can be used to remediate rooms post-infection rapidly, which is why its primary market is medical facilities. These range from doctor surgeries and waiting rooms to hospital operating theatres and wards. “Anywhere there is a need to reduce the risk of cross-infection,” he says.

The efficacy of Novaerus products have been independently tested and verified across a range of pathogens including measles, influenza and C-diff, as well as fungal spores in buildings.

In fact the biggest challenge it faces are lower quality plasma products currently in the market, he says. These operate in a totally different way, typically by sending out ions into a room which are charged to attract pathogens before having them fall to the ground or onto surfaces where they can be disinfected.
Novaerus’s patented technology is entirely unique in killing them, at speed.

As word of its effectiveness has spread, it has witnessed enormous interest across Asia Pacific, including countries such as South Korea, Vietnam and China, where it is currently opening its first office, in Shanghai.

“Our products are aimed at anywhere there are people but we have always found it easier to get our message across in Asia, where people are already very conscious of the risk from pollutants in the external air,” says Dr Devlin.

“There are already a lot of solutions in this market, including ones which use HEPA (high-efficiency particulate air) type filters or masks, but these are effective only for particulates. Again, viruses are much smaller and can pass through them,” he says.

Novaerus machines are effective against hospital ‘super bugs’ and are an inexpensive solution for hospital systems, “particularly given the cost of post-operative infections, such as where a hip replacement has to be done again”, he points out.

Today Novaerus sells into medical facilities in 40 countries, including its main market, South Korea. In October 2019 it signed a partnership in that country which will see its products sell into the high end consumer market too. It’s a first for the company but a move likely to be replicated elsewhere.

“South Koreans are very aware of exterior air quality,” says Dr Devlin. “We launched in that country prior to the current coronavirus outbreak and know that products that are successful in South Korea transfer well around other countries in Asia Pacific.” Already it has seen significant growth in demand throughout the region. “It helps that everything we say about our product is the result of independent tests. It’s not something we are pulling out of the air.”

Aerogen

Ireland races to produce ventilators, nebulisers and more

As the global battle against Covid-19 intensifies, Irish medtech and life sciences firms are ramping up production to meet soaring demand for nebulisers, ventilators and other badly-needed treatment and protection equipment.

Doubling production of critical devices

Half of the existing ventilators in acute hospitals around the world were made in Ireland, which is ranked as one of the top five global medtech hubs.

Medtronic, the world’s largest standalone medical device maker, produces ventilators in a large manufacturing plant in Galway, in the west of Ireland. It is doubling its capacity by more than doubling its workforce of 250 and moving to round-the-clock production.

Another firm increasing production to meet high global demand related to coronavirus treatment is Enterprise Ireland-backed client Aerogen. It’s the world’s leading supplier of aerosol drug delivery products through ventilators to patients in critical and intensive care.

Before the current crisis, Aerogen already provided hospitals in more than 75 countries with its products, benefitting 10 million patients.

Aerogen CEO John Power expects the company could ship 3m or 4m units in 2020, up from 2m in 2019. It is also investigating how to address the global ventilator shortage by adapting non-invasive ventilation systems and are striving to ensure they can meet the sudden and unprecedented growth in demand.

“We are a global company and we are balancing demand from across the world.” says Power

Demand up by as much as 300%

Galway-based M&M Qualtech manufactures products for the medtech, aviation, ICT and other sectors. It produces ventilators, nebulisers and medical monitoring equipment for its medtech customers, including Aerogen and Medtronic. It says it’s seeing capacity demand three to five times higher than the usual pre-crisis level.

M&M Qualtech began to see this spike in manufacturing demand in early March and already expects to produce 4m nebulisers this year, up from 2m last year. It also anticipates a similar rate of increase in production of nebuliser controllers (likely to produce 45,000, up from 35,000) and ventilator AC modules (expecting to make 18,000, up from 5,000 in 2019).

It’s increasing capacity by focusing factory production on the most critically needed medical products, hiring up to 25% more Production Operators, engaging with suppliers daily to expedite materials into production, and redesigning its factory to meet social distancing requirements.  

Ripple effect of Covid-19 crisis 

Also based in the west of Ireland, Vitalograph is the world leader in the analysis of cough drug trials. It specialises in cardiorespiratory and related devices that measure lung and cardiac function, diagnose lung disorders and also produces associated products and software.

Vitalograph is working to meet increased demand for spirometers and consumables such as bacterial-viral filters and test kits and seeing a significant increase in orders of remote monitors. Over the past 15 years, Vitalograph remote monitoring has mainly been used in clinical trials but is now rapidly being adopted by mainstream healthcare.

According CEO, Frank Keane, “Remote monitoring enables the most vulnerable patients with conditions such as COPD, cystic fibrosis and IPF to remain in their homes and not travel to hospitals or clinics and risk picking up infections,”

“As the patients we serve will be the most vulnerable to a respiratory disease of this nature, we are doubling our efforts to ensure we can fulfil our mission and serve them at this time.” said Keane,

Vitalograph has also recruited more staff, and increased both capacity and orders from sub-suppliers, and activated their comprehensive business continuity plan.

Deirdre Glenn, Head of Lifesciences with Enterprise Ireland, said “In the face of the Covid-19 pandemic, Irish medtech companies are rising to the challenge of meeting the increased global demand for essential equipment needed for the treatment and prevention of Covid-19. As the second largest exporter of medtech products in Europe, and with the highest number of people per capital employed in medtech in Europe, Ireland is primed to play its role in the global fight against Covid-19”

Anne Lanigan Enterprise Ireland

Market Watch – A view from the Eurozone

Anne Lanigan, Director of the EurozoneThere is no doubt that the impact of COVID-19 on mainland Europe has been profound with most countries operating on a skeleton crew of essential businesses and services. However, Anne Lanigan, Regional Director, Eurozone, for Enterprise Ireland, says goods are still moving and it is possible to do business.

 

Key Takeaways:

  • The situation is evolving daily and the 45 strong Enterprise Ireland team on the ground in the Eurozone are working and available as normal, albeit remotely to be of assistance.
  • Business is still moving although slower, particularly in the Medtech, Pharma, Construction, Food, eCommerce and other services sectors.
  • The innovation, flexibility and commitment of Irish companies will help them survive this crisis.

 

“A lot of sectors have been very badly hit, particularly in the hospitality, aerospace and automotive sectors,” she says. “High tech construction of pharma facilities and data centres is still continuing, with some challenges in Germany and the Netherlands. Pharma, Medtech and Food still continue as best they can, and we have good examples of clients in the technology, eCommerce and employee engagement sectors who are experiencing growth. However, for many sectors things are likely to get worse before they get better.”

“I would encourage Irish exporters to make contact with customers, partners and distributors. Communication is crucial at this point. Getting an understanding of the situation your customers are in will help you in forward planning and may help you to deliver an immediate or different solution. In addition, the contact you make now will be appreciated and remembered once we are over this crisis.”

Speaking to customers over the telephone or in a virtual meeting, rather than by email, will offer a much better opportunity to engage and get insights into their situation, what their future plans are and how you might feature in those future plans.

Depending on staff availability and the level of slowdown, Lanigan says some businesses may be able to use this time to build their export capability.

“This could be an opportunity to do market research, a very important element of successful exporting” she advises. “This crisis is temporary so fundamentally it’s still important to validate markets and sectors for your products and services, carry out competitive analysis, build a pricing and communication strategy and develop a strong market development plan.

Doing an online language course for an hour every day might also be a welcome break away from home working while also building up a necessary skillset for exporting to Europe.”

The Eurozone director says there are many supports available to Enterprise Ireland clients as well as government supports available to all companies. These can be found on the Enterprise Ireland Covid-19 business response pages and new supports will be added as soon as they become available. Specific market supports such as the Market Discovery Fund are of course still all available. And Eurozone Market Advisors can provide specific information on supports available locally in their markets.

“Alongside the obvious market challenges, we are seeing a number of other challenges. Our clients are in some cases finding it difficult to engage with customers who are busy trying to resolve their own internal problems,” she says. “Movement of product is also more complicated as extra paperwork is required in some locations. It’s also difficult to get clarity regarding the movement of people as the situation is evolving. However, we continue to assist client companies in meeting buyers (virtually), and we are seeing business deals– it’s not anything close to normal but it is still moving.”

“In addition, in every crisis there are opportunities. Irish companies are typically highly innovative and are quick to pivot. Our clients are known for their flexibility and can change focus quite quickly so there is the possibility to adapt products and services to win business in new markets and new sectors.

Lanigan says the key to surviving this crisis is to stay close to customers, demonstrate flexibility, and be innovative:

Markets will start to open again so we need to ensure that we are ready to get going when we come out of this crisis.”

“Enterprise Ireland Market Advisers are available to help. Our team across the Eurozone are working remotely and contactable by phone or email for one-to-one support. Our priorities are to respond to particular requests from clients and to proactively support clients to continue to do business. In addition to supporting contact with customers, distributors and partners, Market Advisors can also provide advice and help with local market knowledge on the evolving situation and help deal with particular issues as they arise. If you haven’t had recent contact with your Enterprise Ireland Market Advisers please get in touch with your Development Adviser who will make the introduction.”

Irish companies are known across Europe for being innovative, flexible, easy to work with and committed. These characteristics will stand to us and help us through this difficult period.” says Lanigan.

 

Private Healthcare webinar

Private Healthcare – UK webinar

Private Healthcare UK webinar

This webinar gives an in-depth analysis of the UK private healthcare market, providing Irish businesses with insights into the opportunities and challenges that exist for companies aspiring to target the market.

Topics discussed in this webinar include:

– Market size and scope.

– Private Healthcare landscape and sectors.

– Digital health usage across the private sector.

The webinar is hosted by Martin Bell, Independent Healthcare IT Consultant.

Martin is joined by James Maunder, Chief Information Officer at The London Clinic for an interactive question and answer session.

 

Irish innovation working to combat Covid-19

Irish companies are taking up the fight against Covid-19. New developments rapidly emerging from Ireland, one of the leading medtech hubs in the world, are being used to help stem the advance of the virus.

 

New rapid Covid-19 diagnostic test

Dublin based HiberGene Diagnostics develops and manufactures molecular diagnostics tests for human infectious diseases. It specialises in the manufacture of rapid and highly accurate testing solutions that are cost effective and simple to use.

Now it is developing a new and rapid test for the novel coronavirus, which it hopes to bring to market shortly after clinical evaluation at potential sites in China, Italy & Ireland.

HiberGene’s tests are based on non-invasive human samples such as swabs, and minimal sample processing.

Because the test for the new coronavirus is a “near patient test”, samples will be taken and tested on location, without needing to be sent offsite to a laboratory, it expects to diagnose a positive COVID 19 result in approx. 20 minutes, many times faster than the fastest existing molecular diagnostic tests.

 

New Protein to fight Covid-19 through diagnosis, vaccines and research

Fellow Irish biotech company Aalto Bio Reagents has launched a new protein with the power to fight the Covid-19 on three fronts – diagnosis, vaccines and research.

Its new recombinant SARS-CoV-2 nucleocapsid protein (code CK 6404) is available for diagnostic test manufacturers, vaccine developers and researchers globally, all of whom are working to stem the current pandemic.

“Patients are currently being screened for the virus by PCR”, explained Philip Noone, CEO of Aalto Bio Reagents, “however there is an important need for serological tests as well to detect all those mild or even asymptomatic cases that may otherwise be missed. Sero-epidemiologic investigations, such as those aimed to better understand transmission characteristics and severity of COVID-19, are also essential.”

The medical field and diagnostic industry have an unrelenting requirement for access to scientifically proven raw materials in outbreak situations like this, where fast diagnosis is required, he said. “With our new SARS-CoV-2 nucleocapsid protein we endeavour to meet this urgent demand.”

Irish company Aerogen has pioneered new ways to help people in respiratory distress. To date more than nine million patients worldwide have benefited from its innovative aerosol drug delivery technology.

Unlike conventional nebulisers, Aerogen has an in-line circuit design, which means the ventilation circuit does not need to be broken for drug delivery. Its management team believes it could therefore be a viable option to help deliver industry-leading care to patients infected with Covid-19.

Its products offer a lower risk of transmission of patient generated infectious aerosol for health care professionals in acute care settings than traditional nebulisers.

For patients requiring ventilation, its vibrating mesh technology, and closed circuit design, makes it a viable option to help deliver industry-leading care. Recent UK government guidelines state that when treating respiratory patients a closed suctioning system must be used, and that ventilator circuits should not be broken unless necessary.

Unlike conventional nebulisers, the Aerogen Solo device has an in-line circuit design and is designed so that the medication reservoir is isolated from the breathing circuit, minimising nebulisation of contaminated fluids.

 

Air Purification System to Kill Airborne Viruses

Pioneering plasma technology developed by Irish company Novaerus is already being deployed to purify air for patients and medical staff.

Novaerus helps control the spread of pathogens by closing the infection control loop made up of hands, surfaces, and now air. It uses a patented technology that kills airborne viruses by sucking air from a room and passing it through patented plasma coils which destroy them, reducing the risk of cross-infection.

Several of its medical-grade, clean air solutions have been donated to hospitals in Wuhan, China.

These include its latest model, Defend 1050, a mobile solution designed for rapid remediation in large spaces and situations with a high risk of infection.

Coronaviruses spread via respiratory droplets produced when an infected person coughs or sneezes, similar to how influenza and other respiratory pathogens spread. “The most difficult disease transmission-route to guard against is airborne because we have very little to protect us when we breathe,” explained Dr Kevin Devlin, CEO at WellAir, the Irish parent company of Novaerus.

 

New Augmented Reality Hand Washing App

Leaders across the world have stressed that the primary tool we have at all our disposal in the fight against Covid-19 is the ability to wash our hands. Stemming the virus’ spread depends on how often, and how well, we do that.

If hand hygiene is done properly it can be over 90% effective in preventing the spread of harmful germs, yet a large number of people are unaware that they are not washing their hands correctly.

SureWash is an augmented reality hand washing app developed to provide proper hand hygiene training to healthcare workers, patients and visitors worldwide.

It ensures compliance in hand hygiene to World Health Organisation protocol by delivering training in an engaging manner that encourages participation. By providing real-time feedback, it helps users to improve their technique.

The software system also provides infection control personnel with the data necessary to monitor hand hygiene progress and to guarantee positive results.

In response to the Covid-19 pandemic it has launched its app to the general public, so that everyone can play their part.

 

New Covid-19 online portal allows GPs to treat patients remotely

Patient portal developer Wellola responded to a call from Ireland’s Health Services Executive (HSE), Ireland’s national health authority, to develop and launch a new secure communication portal for clinicians and primary care providers in response to the pandemic.

Called HSE Covid 19 Portal, it’s an easy to use digital tool designed to optimise doctor and patient safety.  Patients access it via an app which is downloadable via the HSE Covid 19 website. The new online portal allows GPs and healthcare providers to treat people remotely so as to protect themselves from Covid-19. The portal allows GPs and primary-care providers to easily offer patients a range of services, including online bookings, a video consultation service, secure messaging and form completion to assist in triaging.

The Covid 19 app is based on existing technology already developed and tested by Wellola and so was ready to launch just four days after receiving the call from the HSE.

Finally, in the face of a worldwide shortage of life saving ventilators, an international initiative called the Open Ventilator Project quickly came together on Facebook to design and build a 3-D printed ventilator.

In Ireland the project was led by Colin Keogh of Sapien Innovation, a specialist in applied innovation, creativity and design thinking services. Within a week it had produced a prototype it hopes will be validated by Ireland’s health authorities for use in the fight against Covid-19.

Portwest – targeting new markets with GradStart

GradStart

 

Bringing linguistic graduates onboard allowed us to bring in talent that could research Spanish and French speaking territories, and open opportunities for our sales teams, which contributed to our target of 20% growth.

Deirdre Clarke, HR Manager, Portwest

Overview:

  • Portwest is a market leader in the design and manufacture of stylish, comfortable, high-quality workwear that meets recognised international standards.
  • With customer support staff in over 120 countries, the company used Enterprise Ireland’s GradStart initiative to attract fresh graduate talent with French and Spanish language skills to research new markets and drive business activity.
  • The GradStart programme offers salary support of up to 70% for the employment of graduate talent to assist companies when expanding into new markets.

 

1. What attracted you to get involved in GradStart?

We are very fortunate to have a great Development Advisor (DA), who consistently keeps us informed of programs which may be of benefit to our specific business. As we had already taken part in the similar G4IG program, we felt that GradStart would be another fantastic initiative from Enterprise Ireland to help with the development and international growth of our business. At that time we were also in the process of developing a formal Portwest Graduate Program. The timing was ideal for us as GradStart gave us the additional option of introducing a linguistic element to this program.

 

2. What did GradStart allow you to do that you wouldn’t have done otherwise?

GradStart allowed us to provide opportunities to newly qualified graduates at our headquarters here in the West of Ireland, and to include a linguistic dimension to our commercial team which up to now was 100% English speaking. We now have two talented graduates with French and Spanish capabilities who are able to help us explore new market opportunities In particularly across South America and Mexico.

 

3. What challenges and/or opportunities did GradStart help you address?

We had struggled with the exploration of non-English speaking markets. Bringing linguistic graduates onboard allowed us to bring in talent that could research Spanish and French speaking territories, and open opportunities for our sales teams, which contributed to our target of 20% growth. In turn, this allowed us to provide further job opportunities in these regions as we were able to justify the recruitment of sales staff to follow through on the opportunities identified by our graduates.

 

4. Which areas of the business did the graduate contribute to?

Market research and explorative work in heretofore unexplored territories. This is ongoing and while GradStart partially funds the salaries for such graduates for a two year period, we would envisage the continuation of such due to the success of these roles and how the program helps contribute to Portwest’s growth.

 

5. Were there any learnings from your participation in GradStart that you have taken forward into your business.

We have learned that only hiring experienced staff with x years’ experience in x industry can be limiting. Hiring graduates with their fresh approach and up to date knowledge of their areas of expertise can truly contribute in a meaningful way to our corporate goals. Furthermore, the satisfaction of being able to bring these graduates straight from college to management roles within such a short space of time is highly rewarding for any employer. We currently have graduates in managerial positions in our sites in Australia, USA and HQ and will look to add Europe and the UK to this as part of our 2020 Graduate program.

 

6. Would you recommend GradStart to your business peers? If so, why?

This is a fantastic way to introduce a graduate program to your company if you do not already have one. We had previously brought in graduates on an ad hoc basis, but between G4IG and now GradStart, this meant that we were able to formalise a program and become confident in our offering. This is a fantastic opportunity for any graduate looking to kick-start their career and with Enterprise Ireland funding, it is wonderful that businesses can get involved in such a great initiative.

 

7. Which languages were the graduates skilled in?

French and Spanish.

 

8. Have you stayed in touch with the graduate?

Yes – our graduates are still with us as they joined us in September 2019 for a two year period. One graduate will remain on site here at Portwest HQ while the other, following an initial training period at Portwest headquarters, has now relocated to our Kentucky office where they will continue to work with our Sales, Commercial and Marketing teams on exploring new markets. We see this as an ongoing project now, and a model which we would hope to continue after our current GradStart program is complete.

Learn more about GradStart and how it can support your business growth.

Forward-thinking ethos drives Kora Healthcare’s success

It has been an extraordinary year for business across every sector and many companies in Ireland and around the globe have been badly affected by both the pandemic and the onset of Brexit.

But the healthcare industry is one which has managed to stay afloat and even thrive during the crisis as demand for its products and services increased.

Conor O’Daly, CEO of Kora Healthcare, which was originally established in 1994 but ‘reborn’ in 2011 when its sister company was divested and it refocused its sights on a more international market, says the company was fortunate to have been well prepared when the pandemic hit.

“Every business has felt the impact of the crisis over the past 12 months, and we, like everyone else, were taken by surprise,” he says.

“But thankfully we are an organisation which has always worked towards continuous improvement and given our size (32 employees across Irish and UK branches), we were agile and able to adapt easily.” says O’Daly

“When it came to remote working, our IT set-up was thankfully already in place as some staff had been working from home on occasion or internationally and we also have pretty adaptable working methods so rather than hibernating or going into sleep mode, we looked for opportunities. One we quickly seized on was launching our new portfolio of Vitamin D products, under our brand FamilyD, which of course are very front of mind now as every time you open a magazine or put on the TV, people are talking about Vitamin D and its benefits on the immune system given Covid. Fortunately, we had a well-established brand BabyD in the Vitamin D space but were looking to expand the portfolio and recent events gave us the push to do just that.”

 

Preparing for Brexit

The emerging pharma and medical device company, which is based in Swords, has actually increased its head count since the start of the pandemic and thanks to a forward-thinking ethos, has not only survived the current crisis but has also prepared well for Brexit and is coping well with the new regulations.

“Given the industry we are in, there was a huge amount to prepare ahead of Brexit,” says O’Daly. “When the UK left the EU, there were always going to be huge changes with regard to the regulation, control and monitoring of medicines and medical devices and impact to Kora Healthcare. It is a heavily regulated industry, and rightly so, so understanding the finer details and scenario planning became a challenge when there was an information vacuum at times.

“But we started preparing for this right from the start –the day after the Brexit vote was revealed, as we knew there would be a lot involved. We broke down the issues into five broad areas – people, finance, operations, intellectual property, and customs – and looked at how they would impact our business and what we would need to do to ensure a smooth transition and continuation of business.

“We have experienced no issues so far, aside from understanding finer details related to Northern Ireland protocol in the latter months of 2020. But we said from the start that we wanted a ‘no regrets Brexit’, so we prepared for the worst and hoped for the best. And when we got back to work on January 4th, we had to roll back on some of our worst-case scenario preparations. The only thing that still concerns us, and perhaps the industry in general, is UK logistics preparations and movements in and out of the UK.

“Our concern is not our shipment but rather the one in front or the one behind which might not have its paperwork in order and could delay our products getting to our customer” says O’Daly

Looking back over the past 2 ½ years, we have been very proactive to the point that at every opportunity we reflected on and discussed Brexit and its impact.”

 

Taking the step into new markets

Along with preparing well for Brexit, the Dublin-based company also decided to open a branch in the UK, which will ultimately, make doing busines there a lot easier.

“Because we already had a commercial team in the UK and increasing revenue was coming from there, we decided the time was right to scale commercially and establish a firm footing and opened a subsidiary in York,” says the company CEO. “Regardless of the Brexit vote, we felt that it was the right time for us to formally put a structure and more dedicated resources.

“Over 50% of our revenue comes from UK, but also we wanted to grow internationally and have put more resources towards developing in other countries such as Germany and Belgium – and we are also looking to branch out to Canada and the US by hopefully opening an office in Canada to cover that jurisdiction.

“Brexit prepared us for further trade and has made diversification across additional territories much easier. ” 

“Of course, as a company, we have always been internationally driven and market our products in 32 countries, either by ourselves or with partners – so we are not afraid to do business around the world and the reality of Brexit gave us the incentive to push more into Europe, which is what we hope to do next.”

O’Daly says that Enterprise Ireland was also a huge help when it came to developing the business abroad.

“Right from day one, Enterprise Ireland was a fantastic resource for us,” he says. “We got some necessary supports and consultancy advice in the early stages particularly around financial planning, given the impact on exchange rates.

“They also ran some very informative seminars and then in recent months, some very useful webinars. And our development advisor has been in contact on a regular basis to make sure we were working on the things we needed to and to check if we needed any additional support.”

While the team at Kora Healthcare has managed to survive and thrive over the past year, they also have plenty of plans for the future and would advise other healthcare companies who are considering branching outside of Ireland to plan well ahead.

“Things can move very slowly in our industry and when it comes to registering or developing a medicine or therapy, it’s a thorough process – not everything happens as swiftly as the Covid vaccine,” he says. “So I would advise other firms to prepare well in advance. And while the UK is still our closest neighbour and trading partner, so it’s natural for Irish companies to seek to trade with them initially, I would also encourage looking to the Eurozone markets sooner rather than later.

“There will be benefits to ongoing trade with our nearest neighbour, but doing business with the UK may become more cumbersome – so we shouldn’t forget about France, Germany, Italy and Spain – as they are all viable and mature markets which are of similar size or indeed bigger than the UK.”

Evolve UK – New UK importing rules with HMRC – Establishing a UK presence webinar

 

The Evolve UK webinar series highlights the opportunities for Irish companies interested in doing business with the UK.

This webinar examines the upcoming rule changes to importing into the UK with insights from

– Deirdre McPartlin, UK Manager at Enterprise Ireland

– Margaret Whitby, Head of Stakeholder Engagement at BPDG

– Claire Wilson, Stakeholder Engagement at HMRC Customs and Borders unit

– Ruth Potter, Partner at Ecovis

– Gerry Collins, Managing Partner at Ecovis

Access key insights from sectoral experts with the Evolve UK webinar series.

Regulations in the German healthcare sector

    The German healthcare market is the largest in Europe offering ample opportunities for Irish medtech and e-health businesses.

    This webinar is chaired by Enterprise Ireland  Market Advisor Nicol Hoppe and will examine

    • accessing opportunities in the German market

    • the opportunities emerging with digitalisation

    • how to manage budgets and timelines effectively

    with expert insights from:

    • Christoph Bischoff-Everding of HGC

    • Andrea Seidel of Dr. Seidel Lifesciences

    Arab Health

    How Irish – UAE partnerships are shaping the future of healthcare

    Imed Abnoun, market executive for Enterprise Ireland Dubai, outlines partnership opportunities for Irish medtech innovators in the UAE and across the Gulf region.

    Imed Abnoun, Enterprise Ireland Market ExecutiveAs part of its Brexit response, Enterprise Ireland has focused efforts on supporting Irish companies to identify new market diversification opportunities, including the Gulf region, which has become an important market for Ireland. Entering a new export market is an important strategic decision for any company but with the right preparation the rewards can be mutually beneficial.

    The Middle East’s largest healthcare exhibition, Arab Health 2020, took place in Dubai in January, demonstrating that the healthcare sector provides a strong example of how Irish pharmaceutical and medtech companies can enter the market or expand further to meet rapidly rising demand in the UAE and wider Gulf region for world-class innovative products, services and expertise across the full spectrum of the healthcare sector.

     

    Healthcare opportunities in the UAE

    In the UAE alone, this strong demand is clear with market analysis estimating that spending on healthcare will reach $3.6 billion by 2030. Irish healthcare companies are ready to forge new partnerships with healthcare providers in the UAE to provide patients with the latest world-leading innovations that further enhance the patient experience, improve patient outcomes, and supply lifesaving technologies that are used in healthcare systems worldwide.

    Ireland and the UAE already have strong economic ties and mutually beneficial partnerships, including across the healthcare sector. Take, for example, the partnership in Dubai that Martin Dunne, the Director of Ireland’s National Ambulance Service has focused on. Martin has been actively supporting the Dubai Ambulance Service in the provision of training for paramedics, equipping them with world-class life-saving professional training and development. Ireland’s National Ambulance Service, in partnership with the Higher Colleges of Technology in Dubai, provides the curriculum and accreditation for diplomas in emergency medical services that train paramedics and advanced paramedics with life-saving skillsets that benefit Dubai and the UAE.

    The partnership is a good example of health diplomacy in action, through country-to-country institutional collaboration that mutually benefits all parties, both public and private sector and country-to-country bilateral relations, and ultimately leads to lives being saved in Dubai.

    However, the collaboration goes further than education and training. The Dubai Ambulance Service is equipped with cutting-edge Irish hardware and software related to patient and paramedic safety, operational efficiency, and fleet maintenance and diagnostics. Irish company Acetech, a global manufacturer of vehicle intelligence solutions for emergency service fleets, provide this hardware and software.

    At Arab Health 2020, we saw further collaboration between the 14 Irish companies hosted on the Ireland pavilion in the medtech, digital health and pharmaceutical sectors and healthcare providers from across the region – resulting in 10 major contract signings. The companies showcasing their world-leading expertise included:

     

    From its life sciences sector, with a vibrant pharmaceutical industry that exports almost €70 billion annually, through to the innovation of the medtech sector, with exports of €12.6 billion to over 100 countries worldwide, the Irish healthcare industry is a big success story. In the UAE alone, 40% of all Irish goods exports last year were pharma, wellness and medicines-related. Ireland is a global leader in the medtech industry and will seek to leverage its innovative expertise to meet the demand in the region in a sector estimated to be worth $31.6 billion by 2025.

    The UAE and Ireland recognise the significant mutual benefits that arise from collaboration and partnership. Arab Health 2020 added a new chapter to this, helping to shape the healthcare services of both countries to benefit their people.

    Dmac Media Director of Sales

    Dmac Media – attracting new talent with GradStart

    Tech graduates are highly desirable and form a key part of our growth plans.  We had issues competing for that talent and GradStart allowed us to offer a much more attractive package to graduates.”

    Dave McEvoy, Sales Director, Dmac Media

    Overview:

    • Dmac Media is a web design agency offering a full suite of web solutions including web design, eCommerce platforms, content management and digital marketing.
    • With offices in Dublin, Sligo and Cork the company used Enterprise Ireland’s GradStart initiative to attract fresh graduate talent and drive business activity.
    • The GradStart programme offers salary support of up to 70% for the employment of graduate talent to assist companies when expanding into new markets.

    1. What attracted you to get involved in GradStart?

    Tech graduates are highly desirable and form a key part of our growth plans.  We had issues competing for that talent and Enterprise Ireland‘s GradStart allowed us to offer a much more attractive package to graduates.

     

    2. What did GradStart allow you to do that you wouldn’t have done otherwise?

    Bringing in fresh talent to our business allowed us to focus more heavily on business development as a daily activity rather than a paper based plan.

     

    3. What challenges and/or opportunities did GradStart help you address?

    With qualified personnel we had lower training and induction costs this allowed us to keep up in a fast paced sector in a sustainable way.  The challenge (as always) was finding the right graduates.

     

    4. Which areas of the business did the graduate contribute to?

    Our graduates have broadened both our technical skillset as well as our graphic design and process management skills.  The impact was noticeable from day one.

     

    5. How did participating in GradStart impact your business positively?

    GradStart gave us a headstart on developing new products which in turn has brought our entry into new markets considerably closer.

     

    6. Were there any learnings from your participation in GradStart that you have taken forward into your business?

    We have evolved from a company with very standard and fixed methodologies to one that is now willing to experiment and develop better strategies.

     

    7. Would you recommend GradStart to your business peers? If so, why?

    Yes, it gives you time to focus on the business rather than just working in the business.

    Learn more about GradStart and how it can support your business growth.

    Loci Orthopaedics

    How the Innovation Partnership Programme is helping Loci Orthopaedics de-risk product development

    “NUIG has the expertise and the equipment to develop this technology much faster and more efficiently that we would be able to do in-house.”

    Dr. Brendan Boland, Co-founder, Loci Orthodopaedics

    Overview:

    • Galway company Loci Orthopaedics is developing innovative implants to address unmet need in the orthopaedic extremities space.
    • Enterprise Ireland’s Innovation Partnership Programme enabled the company to work with experts in the National University of Ireland, Galway (NUIG) to optimise technology to improve implant fixation.
    • The company will be undertaking its first clinical trials in Europe later this year.

    Case study: Loci Orthopaedics

    ‘Thumbs, shoulders, knees and toes, knees and toes’ is (almost) what the song says, and it more or less sums up the orthopaedic space within which NUIG spin-out company Loci Orthopaedics is operating. Co-founded in 2017 by Dr. Brendan Boland (CEO) and Gerry Clarke (CTO), the multi-award-winning company is targeting the fastest growing area in orthopaedic medicine – orthopaedic extremities.

    “In 2013, I became a fellow in the BioInnovate programme, where I met Gerry. We identified the unmet clinical need of treating upper limb arthritic conditions. That led to the establishment of Loci Orthopaedics and the development of our primary product, the InDx implant, which can mimic the complex motions of the thumb base joint,” explains Boland.

    The company then began work on a second product, a shoulder implant. Recognising that achieving good primary fixation is problematic for patients with poor bone stock, it licensed OsteoAnchor – technology that had been developed by Dr. Noel Harrison of the School of Engineering at NUIG, who is a leader in the field of additive manufacturing (3D printing).

    “The OsteoAnchor technology allows implants to better adhere to the bone by providing a roughened surface that the person’s own bone can grow into….” 

    We felt that this technology fitted our focus but we needed to optimise its effectiveness and de-risk it to give us the confidence to invest in developing new products using it. Having benefitted in the past from excellent support from Enterprise Ireland, we turned to its Innovation Partnership Programme for help,” says Boland.” 

     

    The power of partnership

    The Innovation Partnership Programme enables companies to access expertise within universities and research institutes and covers up to 80% of the cost of a research project. With NUIG’s recently opened Advanced Manufacturing Lab (developed by Dr. Harrison) located just metres from Loci Orthopaedics, it made sense to ask Harrison’s team to lead the Innovation Partnership Programme project.

    “They have the expertise and the equipment to develop the OsteoAnchor technology much faster and more efficiently than we would be able to do in-house,” says Boland.

    Dr. Eimear O’Hara is the technical lead and project manager. “It’s an ambitious six-month project,” she says. “We’re taking a concept implant and doing the design, prototyping and mechanical testing here in the lab, where we have extensive 3D printing capability. The deliverable will be a metal 3D printed shoulder implant.”

    The Innovation Partnership Programme will deliver benefits to both the company and the university.

    “As well as de-risking the technology, the Innovation Partnership Programme validates it to external parties because the project goes through commercial assessment,” says Boland.  “And there’s the potential for the Innovation Partnership Programme collaboration to lead to further innovation.” 

    From NUIG’s perspective it’s the chance to engage with industry to get insights into real world applications of 3D printing and to demonstrate the capability of its 3D metal printer.

    “This kind of collaboration also informs the content of my lectures, helping to keep Mechanical Engineering students up to date about additive manufacturing processes, materials and product design,” says Harrison.

    “It’s the first time we’ve used the 3D metal printer for an industry-based project. We’re hoping that many more companies will be interested in working with us on using our suite of 3D printers, not just in the medtech space but across all manufacturing,” he adds.

     

    The journey to market

    With the combined value of the markets for its shoulder and thumb base implants currently sitting at around US $2 billion, the outcome of the Innovation Partnership Programme project will be an important milestone for Loci Orthopaedics, enabling it to take the next steps on its journey to market.

    “Our primary market is the US and this year we’ll be making a regulatory submission relating to our InDx product in advance of commercialisation in the US in 2021. We’re aiming to do our first clinical trial of InDx in Europe in June and are anticipating commercialisation in the EU in 2022,” says Boland.

    The same process will apply to the shoulder implant, following about two years behind.

    “Meanwhile we’ll have an active in-house innovation and R&D programme. We’ve already secured patents, have four more filed and 16 more in development. Over the next five years we’re hoping to roll out a whole suite of products.says Boland. 

    Until the products hit the market the company will run lean, maintaining just three staff and using manufacturing and processing partners. Financing currently comes from €6 million secured from seed funding, grants and prizes.

     

    The Innovation Partnership Programme experience

    Loci Orthopaedics received a grant of €85,000 from the Innovation Partnership Programme and contributed €16,000 to the project.

    “For a modest sum of money, we are getting a great deal of work done, a good bang for your buck, as they say. Moreover, applying for the Innovation Partnership Programme grant is relatively straightforward and Enterprise Ireland ensures that the IPP agreement clearly sets out what is expected from each party and what each will get out of it, for example, in the area of intellectual property or how new innovations resulting from the project will be handled. This project is enabling us to add to our R&D pipeline and increase our product portfolio,” says Boland.

    Dr. Harrison encourages companies to think big when considering the Innovation Partnership Programme: “A company may have a technical problem that they need help on but they’re thinking about it in terms of their bandwidth. Through the Innovation Partnership Programme, they can get access to a university’s massive suite of equipment, expert personnel and state-of-the-art facilities.”